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After the study period, the ALCAR group demonstrated statistically significant improvements in musculoskeletal pain, depression, and overall quality of life compared to the control group

2.2.3 Autophagy and apoptosis Autophagy is an early cellular response to METH-induced stress and is activated by the mTOR signaling pathway (Kongsuphol et al., 2009)

Here, we demonstrated that the GST tag is a substrate for TG2 and that crosslinking between the GST tag and other TG2 protein substrates is responsible for the formation of GST fusion protein aggregates during pulldown experiments

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