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The remaining 54.1% [95% CI 29.079.3%] of the effect of tirzepatide on UACR appeared to be direct effects of the pooled tirzepatide doses, with unmodeled variables potentially contributing to some extent [96]
Furthermore, it aligns reasonably well with existing evidence, which suggests that the response to this type of treatment is heterogeneous and likely multifactorial
It functions as a cofactor for methylmalonyl-CoA mutase in mitochondrial metabolism
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