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Available: Accessed 10 Feb 2026 Al-Dhahebi A, Ling J, S
doi: 10.1056/NEJMoa1014296 142 NagaiM.NoguchiR.TakahashiD.MorikawaT.KoshidaK.KomiyamaS.et al
(PubMed) Hermann R, Niebch G, Borbe H, et al
They found ALT elevations of up to 8 times the upper limit of normal in 8% of participants, and three times the upper limit of normal in 39% of participants
These factors promote the transcription of the MMP-13 gene by activating the MAPK and NF-B signaling pathways
![Classification of GLP-1 RAs based on different parameters [13]](https://www.researchgate.net/publication/343265981/figure/tbl1/AS:923164464906240@1597110968484/Classification-of-GLP-1-RAs-based-on-different-parameters-13.png)
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