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Educational commentary

Br J Clin Pharmacol 2025 co-infused a GLP-1 agonist with glucagon in healthy young men (Part B, n=12, median age 24): exenatide alone +4 bpm (95% CI 26), low-dose glucagon alone +4 bpm (95% CI 17), and the two together +7 bpm (95% CI 49) at 60 min

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Targeted disruption of the mouse lysosomal acid lipase gene: long-term survival with massive cholesteryl ester and triglyceride storage