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GIP (Glucose-dependent insulinotropic polypeptide): Works in tandem with GLP-1 to enhance metabolic efficiency and reduce systemic inflammation

Liver-derived acylcarnitine can serve as an energy substrate, particularly during prolonged exercise or fasting

Any unexpected symptom that develops after initiating the combined protocol should be evaluated in the context of potential compound interactions

Referral to Tier 3 or Tier 4 Weight Management Services Includes support from a multidisciplinary teamdietitians, psychologists, physiciansfor patients meeting specific criteria