The observed weak or undetectable oxidoreductase activity of ROXY9 was not necessarily expected from the primary sequence, since ROXY9 rather resembles class I than class II GRXs
Secondly, we need to also see if semaglutide benefits patients who have more severe forms of peripheral artery disease. Moving forward, Bonaca hopes other clinicians will inquire more about what their patients with peripheral artery disease are experiencing and take the proper steps to treat them, whether it be through supervised exercise, lowering cholesterol, or offering semaglutide if they also have type 2 diabetes
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