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Front Biol

Chronic stress elevates cortisol, which suppresses GLP-1 secretion and promotes visceral fat accumulation

Most of us have at least heard of antioxidants special substances that promote cellular health by counteracting the effects of harmful molecules called free radicals

In contrast, long-acting agonists (such as albiglutide or dulaglutide, or extended-release exenetide) have a stronger effect to reduce fasting glucose levels mediated by their effect on insulin and glucagon release

But CMS announced in May 2026 that the Part D portion of the BALANCE Model will be delayed indefinitely and that the GLP-1 Bridge will be extended through December 31, 2027

GLP-1 receptor agonists like Ozempic may also have indirect effects on stress and mood