Native Type II collagen peptides have shown remarkable effectiveness for joint health
Note: The review article states much LOWER quantities may be biologically active
It is also utilized for managing the physiological response to stress, balancing cortisol levels, and supporting the bodys natural circadian rhythm
Avoid the inner thigh where large blood vessels run near the surface
A 2019 randomized controlled trial of lipotropic injections (methionine, inositol, choline, B12) versus saline placebo in 120 participants on ad libitum diets found 0.8 kg (1.76 pounds) difference at 12 weeks, not statistically significant (p=0.18) (Karbalay-Doust et al., Journal of Research in Medical Sciences , 2019)
In the nineties, Sikiric licensed the compound to a Croatian company called Pliva, which sought a treatment for ulcerative colitis