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This discrepancy may be attributed to several alternative, non-mutually exclusive hypotheses that must be considered with equal weight: (1) a misalignment between the drugs therapeutic window and the disease stage of the enrolled patients (the prevention hypothesis)

These medications can help many patients feel satisfied with smaller portions, reduce cravings, and improve consistency with healthier nutrition habits

Altered metabolomic-genomic signature: A potential noninvasive biomarker of epilepsy

Dynamic imaging of LDH inhibition in tumors reveals rapid in vivo metabolic rewiring and vulnerability to combination therapy

Consistent Medication Supply Established clinics and medical providers typically have more reliable access to FDA-approved medications

This approach makes the process more motivating and less overwhelming