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Why might GLP-1s affect taste and smell

Upregulation of melanin biosynthesis or increase in the number either of normal or of atypical oral mucosal melanocytes may bring about oral mucosal melanin hyperpigmentation

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Conversely, administration of exendin-9 into the LDTg increases food intake [92]

Because semaglutide already slows gastric emptying, soluble fiber complements this effect by creating sustained, gentle nutrient absorption that reduces hunger swings and energy crashes