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Hair follicles produce sebum, which lubricates and waterproofs the skin, while sweat glands aid thermoregulation

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2.2 Apoptosis of tubular epithelial cell in DKD Aberrant TEC apoptosis has been widely recognized as one of the core pathological events (73)

However, the energy needed to sustain cardiomyocyte physiological activity is supplied by both glucose and FA metabolism, although FA oxidation rather than glucose metabolism is the predominant energy source (Lopaschuk et al., 2010)

Inhibition of glucagon secretion or antagonism of glucagon receptors has become a potentially effective treatment strategy for T2DM patients (Lund et al., 2014)