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Free Cu2+ is toxic (Fenton reactions, hydroxyl radicals), but the GHK-Cu complex is stable, diffusible and delivers copper in a targeted manner to copper-dependent metalloenzymes: lysyl oxidase (collagen/elastin crosslinking), Cu/Zn superoxide dismutase (SOD1, antioxidant defence), tyrosinase (controlled melanogenesis), dopamine-beta-hydroxylase

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doi: 10.1111/dom.13741 53 MehrtashFDushayJMansonJE

If you add too much too fast, you might feel gassy or bloated

It typically results from inadequate insulin secretion because of dysfunction of the insulin-secreting pancreatic beta cells