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Medicaid coverage All state Medicaid programs cover GLP-1s for type 2 diabetes, but weight loss coverage is optional and left to each state

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The most commonly prescribed GLP-1 agonist is semaglutide, which has gained popularity in recent years after the Food and Drug Administration (FDA) approved it for the treatment of diabetes in 2017 (under the brand name Ozempic), for the treatment of obesity in 2021 (under the brand name Wegovy), and for reducing cardiovascular disease risk in 2024 (Wegovy)

They are only recommended for short-term use to reach remission, because they are not effective at preventing flare-ups

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Epalrestat also alleviates subjective symptoms and enhances NCV