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Small uncontrolled semaglutide and tirzepatide series suggest that extending the same dose to every other week can hold much of a plateau with less drug and may preserve more muscle than active loss

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They occur in a smaller percentage of users, but they do happen

Consistent use and adherence to dosage instructions are key

10.1038/ncb3064 41 FuW.MaY.LiL.LiuJ.FuL.GuoY.et al (2020)