While still investigational , the preliminary data are encouraging for those specializing in metabolic and cosmetic outcomes
The practical bit: Typical dosing is 600mg daily, though some studies use higher amounts
The cyclic structure of MT-2 makes it a more potent, non-selective agonist across the melanocortin receptor subtypes (MC1R, MC3R, MC4R, MC5R) in research models, whereas Melanotan I is comparatively more selective for MC1R
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In fact, the inspiration for this article comes from both seeing remarkable anecdotal accounts from people on these drugs, but also the recent trials of Tirzepatide and Taltz showing actual benefit