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Studies in mice found potent antinociceptive (pain-reducing) effects when the peptide was administered directly to the central nervous system
Trends Biochem Sci
Unlike indirect biomarkers, which are affected by alcohol consumption and other potential causes, direct biomarkers only arise from alcohol consumption
Take ghrelin for instance, a peptide connected to hunger that will affect sleep and the release of growth hormone
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Perfusion parameters and biochemical characteristics of the HOPE perfusates The perfusion parameters of N = 11 kidneys, N = 9 for single KT and N = 2 for dual KT, and N = 10 livers undergoing HOPE before the implantation are reported in Table 2
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