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Amos-Landgraf JM, Ji Y, Gottlieb W et al : Chromosome breakage in the Prader-Willi and Angelman syndromes involves recombination between large, transcribed repeats at proximal and distal breakpoints

doi: 10.5223/pghn.2014.17.4.203

Approximately 75-85 percent of patients on prescription GLP-1 medications achieve clinically significant weight loss (at least 5 percent body weight)

At first, another glucose-lowering option

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If lethargy significantly impairs quality of life or daily functioning, a review of the treatment plan may be appropriate