Adults (18 years) with overweight or obesity BMI 30 kg/m2 *OR* BMI 27 kg/m2 with 1 weight-related comorbidity (hypertension, dyslipidemia, obstructive sleep apnea, cardiovascular disease) This trial was for patients without type 2 diabetes Objective of the 2 year trial: To compare the 2-year effect of semaglutide 2.4 mg once weekly, vs placebo, on body weight, cardiovascular risk factors, and glucose metabolism
These are expected effects of the drug class
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B., Drmic, D., Grgic, T., Strbe, S., Zukanovic, G., Crvenkovic, D., Madzarac, G., Rukavina, I., Sucic, M., Baric, M., Starcevic, N., Krstonijevic, Z., Bencic, M
The added glucagon receptor activity contributes energy expenditure effects that the other two compounds dont produce
Evaluation of proposed FDA criteria for the evaluation of radiolabeled red cell recovery trials