10.1111/dom.14990 Summary Keywords cardiovascular disease, major adverse cardiovascular events, semaglutide, type 2 diabetes mellitus, meta-analysis Citation Tan S, Yin Y and Lu J (2025) Effects of subcutaneous or oral semaglutide on cardiovascular outcomes in patients with type 2 diabetes mellitus: a meta-analysis of randomized controlled trials
We postulated that if depletion of the UMP/UDP/UTP pool is driving this stress, then we would see similar effects with a DHODH inhibitor, BAY-2402234 (ref
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To estimate the comparative effect of GLP-1RA on the risk of SIS, we employed a new user, active comparator design and we carried out multivariable Cox regression modelling with inverse probability of treatment weighting (IPTW) based on propensity scores