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Ethics statement The studies involving humans were approved by Ethics Committee of Beijing Anzhen Hospital of the Capital University of Medical Sciences

[27] He then spent three years on fruitless efforts to persuade the pharmaceutical industry to develop exendin-4 into a drug

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It plays a crucial role in cellular events such as inflammatory responses, altered cell growth, and apoptosis ( Figure 1 ) ( Figure 1 The role of alterations in the antioxidant system in the pathogenesis of vitiligo has been extensively studied ( CAT gene and reduced catalase activity have also been associated with several metabolic diseases, such as diabetes, hypertension, and peroxisomal/peroxisomal diseases ( On the other hand, the chronic OS will produce an excessive accumulation of ROS, which in turn induces the production of damage-associated molecular patterns (DAMPs) and the release of melanosomal antigens that activate innate immunity ( + T cells are activated through HSP70i activation and antigen presentation by mature dendritic cells ( + T cells are recruited to induce melanocyte apoptosis ( + T cells ( These findings suggest that oxidative stress plays a vital role in the pathogenesis of vitiligo

Int J Mol Sci 22:5228 Shtossel O, Koren O, Shai I, Rinott E, Louzoun Y (2024) Gut microbiome-metabolome interactions predict host condition

The emergence of intelligent, responsive nanocarriers may help NADs interact with complex environmental changes, responding to specific in vivo changes, such as pH, redox conditions, or external stimuli (ultrasound, light, magnetic fields, and electric fields)