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Treatment with 5-Amino-1MQ combined with diet transition produced dramatic whole-body adiposity and weight loss, rapidly normalising these measures to levels comparable to age-matched lean control animals an outcome that diet switch alone was unable to achieve in the same time frame

[1] It is important to be precise about the grammar of that sentence: every clause in it describes a hypothesis advanced by the compounds proponents , not a settled fact of human physiology

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5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) used in metabolic research

AOD-9604 and Weight Loss Research has shown that AOD-9604 can stimulate lipolysisthe breakdown of fatand inhibit lipogenesis, the transformation of non-fat food materials into body fat