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Ferenci P, Lockwood A, Mullen K, et al

The only reason that system of rebates even came to exist was to create enticements so certain manufacturers could persuade pharmacy benefit managers and employee-sponsored health plans to favor their drug over others

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Extended-duration effects of GLP-1 RAs and multi-agonists on liver-associated outcomes involving cirrhosis development, HCC incidence, and death from hepatic causes are being elucidated through ongoing observational studies and long-term trial extensions [65-70]

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The safety profile showed modestly elevated rates of overall side effects and drug-attributable side effect in the efinopegdutide cohort relative to semaglutide, attributable predominantly to a higher frequency of gastrointestinal manifestations [52]