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Different GLP-1 RA have different dosing requirements, such as: Before Meals: Oral semaglutide (Brand name: Rybelsus) taken 30 to 60 minutes before meals Once-daily injections: Lixisenatide (Brand name: Adlyxin) Liraglutide (Brand names: Victoza, Saxneda) Once-weekly injections: Dulaglutide (Brand name: Trulicity) Semaglutide (Brand name: Ozempic) Extended-release exenatide (Brand names: Bydureon, Bydureon BCise) Naturally produced GLP-1 RAs versus GLP-1 Therapies The natural hormone, called endogenous GLP-1 RA produced by the body is released in response to glucose
Weekly injection scheduler (Ozempic/Wegovy) Pick one anchor: Sunday night after brushing teeth Monday morning after shower Friday after work (before weekend travel) Then add redundancy: Calendar event (recurring weekly) Phone alarm Keep supplies in one visible place Checkin points: Because Ozempic and Wegovy titrate in 4week steps on the FDA labels, set a recurring checkin every 4 weeks to review side effects and adherence (FDA Ozempic label, 2025
Clinical consensus suggests a two-pronged strategy to preserve lean muscle mass while maximizing fat loss
However, the two classes of agents differ largely in their pharmacological modes of action on glucose-lowering and CV parameters
References: Smith, R
Patients who maintain results long-term describe: Significantly less food noise
