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Boehringer Ingelheim / Zealand Pharma (ZLDPF): Survodutide (aka BI 456906) [44] [44] In a placebo-controlled study evaluating the GLP1R/GR dual agonist (Obesity Indication), patients received weekly subcutaneous injections of 4.8mg for a duration of 46 weeks

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Protein has a higher thermic effect than carbohydrates or fat, and inadequate intake accelerates muscle loss during caloric restriction

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Elevated IGF-1 levels have been associated with increased risk of certain cancers, fluid retention, and joint pain