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Raun, K., Hansen, B., Johansen, N., Thogersen, H., Madsen, K., Ankersen, M., & Andersen, P

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Microglial depletion with clodronate liposomes increases proinflammatory cytokine levels, induces astrocyte activation, and damages blood vessel integrity

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Typical protocols involve evening dosing to align with natural GH release cycles

Cagrilintide (developmental code NNC0174-0833) is a lipidated, long-acting analogue of human amylin, developed by Novo Nordisk