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Medical Hypotheses, 68 (5), 1026-1034
The PDE6 mutation in the rd10 retinal degeneration mouse model causes protein mislocalization and instability and promotes cell death through increased ion influx
Enzymatic oxygen scavenging for photostability without pH drop in single-molecule experiments
In addition, chicken breasts are an excellent source of lean protein
PMID 18347346
Collectively, these studies highlight multiple pharmacological strategies to disrupt FSP1 function, including active-site inhibition, species-selective targeting and structure-guided inhibitor development
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