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Studies have reported OCTN2 expression in respiratory epithelial cells and alveolar macrophages, which is especially high in the upper lung region [301], and OCTN2-mediated carnitine uptake plays an important role in maintaining respiratory cilia beating and airway mucociliary clearance function, helping to remove excess mucus and potentially harmful substances from the airway [302]
Forming an exercise habit is a process that takes time and patience
Strong pharmacovigilance, physician-led prescribing, patient education, and real-world evidence generation will be critical to sustain long-term trust in this therapeutic class
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