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Defining the Phenotypic Spectrum of SLC6A1 Mutations. Epilepsia, vol

doi:10.1038/ejcn.2014.281

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Continuous oxidative stress can lead to chronic inflammation, intense cytokine release and a cytokine storm as seen in SARS-CoV-2 infection in COVID-19 disease, and the viral infection enhances oxidative stress creating a fatal vicious circle between oxidative stress and cytokine storm during COVID-19 infection (Delgado-Roche and Mesta, 2020

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Its primarily produced in the intestines, pancreas, and hypothalamus area of the brain