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the British Medical Journal also argues that preserving muscle mass and physical function should also be a central goal of obesity treatment instead of focusing only on weight loss

Tirzepatide contributed 48,649 more life-years gained per 100,000 people, and semaglutide generated 35,634 more life-years gained per 100,000 people than lifestyle intervention alone

If your overall intake drops by a third, and you weren't eating enough protein to begin with, you're now in a deficit that your body will make up for by breaking down muscle tissue

timing protein intake shortly after workouts further amplifies muscle-preserving signals