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Treatment of Pla2g6 / mice with semaglutide significantly increased CREB mRNA levels compared to untreated Pla2g6 / mice and restored expression levels to those observed in the wild-type controls

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Glycyrrhizin, particularly its derivative DG, alleviates the pathological progression of alcoholic fatty liver by regulating the Src Homology Region 2 Domain-Containing Phosphatase (SHP)1/Spleen Tyrosine Kinase (SYK) signaling pathway in macrophages, thereby inhibiting hepatic oxidative stress, inflammatory responses, and pyroptosis (Zhang, 2023) (Table 3)