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Elsevier Science Publishers BV, Amsterdam, pp 309354
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Oral semaglutide (Rybelsus) is preferred by some patients over injectable options like Ozempic due to its convenience, ease of use, and avoidance of needles
Weight loss is marketed as metabolic optimization. Semaglutide is framed as a tool for sustainable change. TikTok influencers film their GLP-1 journeys like skincare transformations, while companies build identity-driven narratives around empowerment and self-betterment
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Unanswered Questions Regarding Weight Loss Mechanisms: Perspectives to Preclinical Research The exact mechanisms underlying the weight loss are still not clear, especially in light of the enhanced effects seen with multi-agonism, despite the large number of incretin agonists presently undergoing clinical trials and their remarkable effectiveness in managing obesity and T2DM [5, 14, 146, 147]
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