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Research suggests approximately 60-70% of tirzepatide-induced weight loss comes from reduced food intake, with the remaining 30-40% attributable to improved fat metabolism and energy expenditure

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"CagrilintideSemaglutide in Adults with Overweight or Obesity and Type 2 Diabetes"

It was originally developed as an anti-obesity drug candidate because early research suggested it could stimulate lipolysis (fat breakdown) and reduce lipogenesis (fat formation) without the typical growth-promoting or IGF-1raising effects of full HGH