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Sport Compliance: Falls under the World Anti-Doping Agency's (WADA) S0 classification, meaning all non-approved substances are prohibited in competition

Since adipose tissue is responsive to endotoxins, bacterial translocation may provide a mechanism whereby the gut microbiome can modulate the adipose metabolome (for review, Kruis et al., 2014 23 ) and consequently exacerbate obesity and its related comorbidities

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Cagrilintide (trials): once-weekly subcutaneous administration, escalated gradually over roughly six weeks to limit gastrointestinal effects