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Shea MK, Holden RM
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As CYP8B1 acts to catalyze 12-hydroxylation and is required for CA synthesis, it serves as a master regulator for the BA composition
Littmann, E
Furthermore, NRF2 controls genes encoding enzymes governing different metabolic pathways, such as lipogenesis and lipid degradation, lipid transport and uptake, enzymes of the pentose phosphate pathway, and some enzymes of glycogen metabolism, like glycogen branching enzyme (GBE) and phosphorylase b kinase subunit A1 (PHKA1), recently linked to NRF2 signalling in the muscle [165] (Fig
118 StaalF
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