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Topical application of GHK-Cu has emerged as a clinically supported strategy to replenish this deficit and restore youthful skin function

[2] Commercially it is made using one of a number of types of bacteria

Human safety data for injectable, oral, or high-dose systemic GHK-Cu is essentially absent this route is unapproved and not supported by controlled trials

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For instance, pegylated FGF-21 analogs have demonstrated promising results in treating NAFLD [279], while recombinant FGF-21 (rFGF-21) has demonstrated the ability to ameliorate BBB damage caused by T2DM [286]

10.1111/j.1600-0714.1995.tb01136.x 22 GherasimC.LofgrenM.BanerjeeR