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Brain fog and memory gaps

When your friend does it, check in

To further evaluate T-cell metabolic transcriptional programs in an independent cohort, we analyzed GSE189536, a kidney allograft biopsy single-cell/CITE-seq dataset containing transcriptomic libraries from 5 TCMR and 3 non-rejection biopsies

Were here and were local

Using in silico design, structureactivity relationships (SARs), chemical optimization, cell-based assays and in vivo experiments, we identified and characterized the first-in-kind small-molecule inhibitors of STX7Munc13-4-dependent endosomal maturation and signaling for use in immune cells that contribute to systemic inflammation

The discontinuation of danuglipron was a significant strategic setback, leaving Pfizer without a GLP-1 programme in the world's fastest-growing peptide market