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doi: 10.3389/fimmu.2017.00521 50 RomaldiniJHBiancalanaMMFigueiredoDIFarahCSMathiasPC

This approach provides both the systemic gene expression modulation from injections and concentrated local delivery from topical application

Route of administration is split between subcutaneous and oral, while major applications include type 2 diabetes mellitus, obesity and other metabolic indications

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