Deficiencies in Vitamin B12 have many side effects but mainly consist of elevated rates of DNA damage with links to general weakness, loss of balance, depression, and anemia
All the outcomes were analyzed with the use of a Cox proportional-hazards model with randomized group assignment as a categorical fixed factor
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Even if administered separately, co-administration without formal pharmacokinetic and pharmacodynamic evaluation cannot be considered safe
Osman AT, Sharkawi SMZ, Hassan MIA, Abo-youssef AM, Hemeida RAM (2021) Empagliflozin and neohesperidin protect against methotrexate-induced renal toxicity via suppression of oxidative stress and inflammation in male rats
doi: 10.2174/0118715206302216240628072554 77 KuilmanTMichaloglouCVredeveldLCWDoumaSvan DoornRDesmetCJet al