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Over-the-Counter Medicines That Help If lifestyle changes arent enough, several medicines can provide relief: Antacids (Fast Relief): Tums, Rolaids, Alka-Seltzer Work in minutes Good for quick relief after eating Effects last about an hour H2 Blockers (Longer Relief): Famotidine (Pepcid), Ranitidine (Zantac 360) Take a couple hours to work Provide relief most of the day Can take before meals or at bedtime Proton Pump Inhibitors (Strongest Relief): Omeprazole (Prilosec), Esomeprazole (Nexium) Block acid production in your stomach Best for frequent or severe heartburn May need a prescription for stronger doses Always talk to your doctor before starting any new medicine, even over-the-counter ones

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Notably, overexpression of GCLC appeared to attenuate these motor deficits, suggesting its protective effect against MPTP-induced motor dysfunction (Fig

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