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Glutamine is a protein that provides energy for the TCA cycle by metabolically degrading glutamine and generating ROS
It plays critical roles in protecting the body from oxidative stress, maintaining cellular functions, and supporting healthy immune function.[1,4] Many factors can increase cellular exposure to oxidative insult, and therefore increase cellular consumption of nutrients-such as glutathione-that provide antioxidant activity
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Ferroptosis activators can also make prostate cancer cells more sensitive to DDP [42]
Treatment follows the mitochondrial support stack protocol, individualized to the specific deficiencies identified and calibrated to the patient's current energy envelope
Original studies were prioritized when they directly examined how amino acid metabolic pathways regulate macrophage polarization, inflammatory function, or disease-associated immune phenotypes in in vitro systems, animal models, or human samples
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