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Although significant progress has been made in understanding the molecular mechanisms underlying APAP hepatotoxicity, there is still an urgent need to find novel and effective therapies against APAP-induced acute liver failure

Available from: Bettge K, Kahle M, Abd El Aziz MS, Meier JJ, Nauck MA (2017) Occurrence of nausea, vomiting and diarrhoea reported as adverse events in clinical trials studying glucagon-like peptide-1 receptor agonists: A systematic analysis of published clinical trials

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Tirzepatide is a new dual GIPR/GLP-1R agonist recently approved by both the European Medicines Agency and the FDA

It promotes fibroblasts and collagen production Fibroblasts are biological cells needed to maintain the structural framework of body tissues like tendons and ligaments