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64,65 In particular, because CKD contributes to the progression of cardiovascular disease through many pathways, the authors of a 2021 review published in Circulation stated that CKD mimics an accelerated aging of the cardiovascular system. 66 Blood Clot and Bleeding Risks Chronic kidney disease increases the risk of bleeding events as well as blood clots (thrombosis) and related health problems
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82,83 GPX1 is shown to promote proinammatory cytokine production and neutrophilia in response to endotoxin, 84 and to contribute to the development of ovalbumin-induced allergic asthma
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