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Patients experiencing new or bothersome urinary symptoms while taking semaglutide should not assume the medication is directly responsible

Furthermore, TMAO alleviated the formation of aortic atherosclerotic lesions in ApoE -/- mice

[70] found in vivo and in vitro studies that GLP-1 and its analog exendin-4 were able to induce an increase in ABCA1 mRNA, increase the expression of apo AI mRNA and promoter, thereby increasing apo AI secretion, indicating that GLP-1 in hepatocytes may mediate the outflow of intracellular cholesterol to apo AI through the ABCA1 pathway

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& Cherry, K