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Not necessary, but refrigeration is acceptable if it prevents temperature fluctuations (never freeze)
Those who are more deficient in Vitamin B12 may report faster recovery time as their symptoms are more noticeable and improvements are detected earlier
Pei, J., Pan, X., Wei, G., & Hua, Y
The 28 days comes from USP and CDC, applied to the whole multi-dose vial category
4 KL1 enhances antibiotic killing in human primary neutrophils
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