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Phase II randomized study of Plitidepsin (Aplidin), alone or in association with L-carnitine, in patients with unresectable advanced renal cell carcinoma

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These effects may be connected to modulation of growth hormone and IGF-1 signaling, as well as alterations in hepatic urea cycle enzyme activity

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L-Carnitine is an amino acid that plays a vital role in the metabolism of fat, and aids in the release of stored body fat and triglycerides into the bloodstream for energy

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