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Diet and exercise must be considered as the first line of treatment, however if they fail to correct metabolic signalling, IGF-1 therapy seems to be promising at metabolic harmonisation

Metabolic effects of social isolation in adult C57BL/6 mice (in Eng)

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Importantly, at study completion, 5A-1MQ-treated mice had a lower fat mass than the obese WD controls and their vehicle-treated counterparts and were not significantly different (with FDR correction) from the LD control mice (Fig

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