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It activates the GIP receptor with approximately equal potency to native GIP, but activates the GLP-1 receptor with roughly five times lower potency than native GLP-1

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This study also highlights how GHK-Cu influences gene expression related to regeneration and healing, making it broadly active in skin, connective tissue, and organ repair

44 Thus, the extrinsic landscape, including immune architecture, stromal interactions, and pharmacologic variables, functions as a dynamic determinant of drug resistance