GLP-1 agonists (semaglutide, tirzepatide) are often covered for diabetes and increasingly for obesity if you meet BMI criteria and have related comorbidities
Tirzepatide is administered subcutaneously once weekly at doses ranging from 2.5 mg to 15 mg, with gradual dose escalation recommended to minimize gastrointestinal adverse effects
While these symptoms can be uncomfortable, they are generally more predictable and less varied compared to those caused by GLP-1 therapies
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The extended pharmacokinetic profile allows therapeutic GLP-1 receptor activation throughout the day and night, providing continuous metabolic benefits rather than the transient effects of native GLP-1
To alleviate the high costs affecting consumers, health-care leaders need to come to the table to address the friction preventing greater access and affordability