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Lovelle explains that glucagon-like peptide-1 (GLP-1) is a naturally occurring hormone crucial for regulating blood sugar, appetite, and insulin secretion. Synthetic versions like semaglutide and tirzepatide have demonstrated remarkable efficacy

Effect of astragalus Polysaccharides on Rats with Non-alcoholic Fatty Liver Disease

Proc Natl Acad Sci USA (2011) 108:62527

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This potentially leads to limitations in GLP-1 receptor agonist use in patients who are unwilling or unable to administer these medications subcutaneously

GLP-1 is one of the gut hormones that profoundly affects glucose regulation by promoting post-prandial insulin secretion, and GLP-1 based drugs are approved for the treatment of T2D (74)