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Description

Muromonab-CD3 (OKT3) is a murine anti-human IgG2a monoclonal antibody targeting the CD3 receptor complex on T lymphocytes, originally approved intravenously for preventing organ transplant rejection but repurposed for UC treatment with an oral version (86)

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Journal of Pharmacology and Experimental Therapeutics, 329 , 1110 1116

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He only fully appreciated its relevance once Dupr demonstrated that GIP suppressed insulin three years later (Brown

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